Carotid endarterectomy (CEA) continues to be widely regarded as the preferred method for carotid revascularization and stroke prevention. The primary goal of CEA is to mitigate the risk of cerebral infarction resulting from carotid stenosis, which aims to alleviate neurologic symptoms, minimize perioperative complications, and improve the overall quality of life for affected individuals. The lack of standardization in anesthesia technique while performing a CEA warrants further investigation of whether general or regional anesthesia is superior in preventing suboptimal cardiac postoperative events. The purpose of this Doctor of Nursing Practice (DNP) scholarly project was to examine the incidence of adverse postoperative cardiac outcomes in relation to anesthesia technique and analyze relationships between negative cardiac events and patient-specific risk factors through secondary data analysis of the National Surgical Quality Improvement Program (NSQIP) database. The search was narrowed to patients ages 18-90 years old who underwent a CEA during 2022. Results indicate there was no statistical difference in the incidence of MI (p=0.644) when comparing GA vs. RA. There was no statistical difference in the incidence of cardiac arrest (p=0.082) when comparing GA vs. RA. Patient-specific risk factors associated with the incidence of cardiac arrest and MI were history of CHF (p<0.001), increased BMI (p=0.039), diabetes (p=0.016), and dialysis (p=0.043). Cox & Snell R Square and Nagelkerke R Square indicated that the model can explain only 0.4-3.3% of the variance, suggesting weak influence. This is further supported by the AUC ROC=0.639, suggesting that the model can only correctly classify CDMI in 63.9% of cases. The findings of this study were included in a manuscript submitted for publication to enhance anesthesia providers' knowledge of the risks associated with local and general anesthetic approaches for patients undergoing CEA. Recommendations for future DNP projects include analyzing NSQIP data over a duration exceeding one year to confirm our findings that patient-related risk factors may contribute to a heightened risk of cardiac morbidity and mortality.